PUBLICATIONS (undergraduate students are underlined)

Leo Pezzementi, Cybil Geiss, William King, Nicolas Lenfant, and Arnaud Chatonnet. 2015. Molecular characterization of an acetylcholinesterase from the hemichordate Saccoglossus kowalevskii. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 181, 50-58.

Leo Pezzementi, Eric Krejci, Arnaud Chatonnet, Murray Selkirk, and Jacqui Matthews. 2012. A tetrameric acetylcholinesterase from the parasitic nematode Dictyocaulus viviparus associates with the vertebrate tail proteins PRiMA and ColQ. Mol. Biochem. Parasitol. 181, 40-48.

Leo Pezzementi, Florian Nachon, and Arnaud Chatonnet. 2011. Evolution of acetylcholinesterase and butyrylcholinesterase in the vertebrates: an atypical butyrylcholinesterase from the medaka Oryzias latipes. PLoS One, 6, e17396

Leo Pezzementi and Arnaud Chatonnet. 2010. Evolution of cholinesterases in the animal kingdom. Chem. Biol. Interact., 187, 27-33.

Brian Perrin, Melissa Rowland, Matthew Wolfe, Igor Tsigelny, and Leo Pezzementi. 2008. Thermal denaturation of wild type and mutant recombinant acetylcholinesterase from amphioxus: effects of the temperature of in vitro expression and of reversible inhibitors. Invert. Neurosci., 8, 147-155.

Melissa Rowland, Igor Tsigelny, Matthew Wolfe, and Leo Pezzementi. 2008. Inactivation of an invertebrate acetylcholinesterase by sulfhydryl reagents: A reconsideration of the implications for insecticide design. Chem. Biol. Interact., 175, 73-75.

Adam Frederick, Igor Tsigelny, Francis Cohenour, Christopher Spiker, Eric Krejci, Arnaud Chatonnet, Stefan Bourgoin, Greg Richards, Tessa Allen, Mary Hollace Whitlock, and Leo Pezzementi. 2008. Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide. FEBS J., 275, 1309-1322.

Natalie Jennings, Leo Pezzementi, A. L. Lawrence, and Stephen A. Watts. 2008. Acetylcholinesterase in the sea urchin Lytechinus variegatus: Characterization and developmental expression in larvae. Comp Biochem Physiol B Biochem Mol Biol., 149(3), 401-409.

Leo Pezzementi. 2008. Science for All: The Associated Colleges of the South Story. Project Kaleidoscope. http://www.pkal.org/documents/ScienceForAllACS.cfm, pp. 1-5.

Raj Patel, Rachael Sanders, Lance Brown, Stephanie Baker, Igor Tsigelny, and Leo Pezzementi. 2006. A tryptophan in the bottleneck of the catalytic gorge of an invertebrate acetylcholinesterase confers relative resistance to carbamate and organophosphate inhibitors. Cell Bioch. Biophys., 46, 253-264.

Leo Pezzementi, Melissa Rowland, Matthew Wolfe, and Igor Tsigelny. 2006. Inactivation of an invertebrate acetylcholinesterase by sulfhydryl reagents: the roles of two cysteines in the catalytic gorge. Invert. Neurosci., 6, 47-55.

Leo Pezzementi, Jianxin Shi, David A. Johnson, Zoran Radic, Aileen Boyd, and Palmer Taylor. 2005. Ligand-induced Conformational changes in residues flanking the active site gorge of acetylcholinesterase. Chem. Biol. Interact., 157-158, 413-414.

Leo Pezzementi, Kim Johnson, Igor Tsigelny, Justin Cotney, Andrew Barker, Elizabeth Manning, and Sarah Merritt. 2003. Amino acids defining the acyl pocket of an invertebrate cholinesterase, Comp. Biochem Physiol. B. Mol. Biol. Biochem. 136, 813-832.

Leo Pezzementi and Joy F. Johnson. 2002. A collaborative, investigative recombinant DNA technology course with laboratory. Biochemistry and Molecular Biology Education, 30, 376-379.

James Scott McClellan, William Blake Coblentz, Mathew Sapp, Gabriel Rulewicz, David Isaac Gaines, Ashley Hawkins, Caroline Ozment, Amy Bearden, Sarah Merritt, John Cunningham, Elizabeth Palmer, Amir Contractor, and Leo Pezzementi. 1998. cDNA cloning, in vitro expression, and biochemical characterization of cholinesterase 1 and cholinesterase 2 from amphioxus: comparison with cholinesterase 1 and cholinesterase 2 produced in vivo. Eur. J. Biochem., 258, 419-429.

Leo Pezzementi, David Sutherland, Michael Sanders, Weily Soong, Daniel Milner, James Scott McClellan, Mathew Sapp, William Blake Coblentz, Gabriel Rulewicz, and Sarah Merritt. 1998. Structure and function of cholinesterases from agnathans and cephalochordates: implications for the evolution of the cholinesterases. In Structure and Function of Cholinesterases and Related Proteins, (B.P. Doctor, P. Taylor, D.M. Quinn, R.L. Rotundo, and M.K. Gentry, eds.), Plenum Press: New York, pp. 105-110.

David Sutherland, Scott McClellan, Danny Milner, Weily Soong, Neal Axon, Michael Sanders, Alison Hester, Yu-Hsing Kao, Ted Poczatek, Sheri Routt, Amir Contractor and Leo Pezzementi. 1997. Two cholinesterase activities and genes are present in amphioxus. Journal of Experimental Zoology, 277, 213-229.

Michael Sanders, Bonnie Mathews, David Sutherland, Weily Soong, Harry Giles, and Leo Pezzementi. 1996. Biochemical and molecular characterization of acetylcholinesterase from the hagfish Myxine glutinosa. Comp. Biochem. Physiol. 115B, 97-109.

Leo Pezzementi. 1994. Research in Biology at Primarily Undergraduate Institutions. Council on Undergraduate Research, Collegiate Research Association of Biologists: Asheville, NC, 344 pp.

Jean Massoulié, Leo Pezzementi, Suzanne Bon, Eric Krejci, and François-Marie Vallette. 1993. Molecular and cellular biology of cholinesterases. Progress in Neurobiology 41, 31-91.

Christopher Atkins and Leo Pezzementi. 1993. Developmental changes in the molecular forms of acetylcholinesterase during the life cycle of the lamprey. Comparative Biochem. Physiol. 106B, 369-372.

Leo Pezzementi, Michael Sanders, Todd Jenkins, Dan Holliman, Jean-Pierre Toutant, and Ronald J. Bradley. 1991. Structure and function of cholinesterase from amphioxus. In, Cholinesterases: structure, function, mechanism, genetics and cell biology (J. Massoulié, F. Bacou, E. A. Barnard, A. Chatonnet, B.P. Doctor, and D.M. Quinn, eds.). American Chemical Society: Wash., D.C., pp 24-31.

Howell Heflin/Leo Pezzementi. 1990. Remarks of Dr. Leo Pezzementi, Birmingham-Southern College. Congressional Record-Senate S10899.

Leo Pezzementi. 1990. NIH AREA Program from the perspective of undergraduate research. Council on Undergraduate Research Newsletter 11, 57-60.

Leo Pezzementi, Hugh C. Nickson, Robert Dunn, and Ronald J. Bradley. 1989. Molecular forms of acetylcholinesterase from the skeletal muscle of the ammocoete of the lamprey Petromyzon marinus. Comp. Biochem. Physiol. 92B, 385-387.

Leo Pezzementi, Hugh C. Nickson, and Ronald J. Bradley. 1988. Lamprey brain contains globular and asymmetric forms of acetylcholinesterase. Neurochem. Int. 12, 131-135.

Leo Pezzementi, Ellen J. Reinheimer, and Maureen Pezzementi. 1987. Acetylcholinesterase from the skeletal muscle of the lamprey Petromyzon marinus exists in globular and asymmetric forms. J. Neurochem. 48, 1753-1760.

Scott W. Melanson, Chang-Hyon Yun, Maureen Pezzementi, and Leo Pezzementi. 1985. Characterization of acetylcholinesterase activity from Drosophila melanogaster. Comp. Biochem. Physiol. 81C, 87-96.

Mark Schneider, Bih-Hwa Shieh, Leo Pezzementi and Jakob Schmidt. 1984. Trifluoperazine stimulates acetylcholine receptor synthesis in chick skeletal muscle cell cultures. J. Neurochem. 42, 1395-1401.

Bih-Hwa Shieh, Leo Pezzementi and Jakob Schmidt. 1983. Extracellular potassium and the regulation of acetylcholine receptor synthesis in chick skeletal muscle cell cultures. Brain Research, 259-265.

Leo Pezzementi and Jakob Schmidt. 1981. Ryanodine alters acetylcholine receptor synthesis in chick skeletal muscle cell cultures. J. Biol. Chem. 256, 12561-12564.

Leo Pezzementi and Jakob Schmidt. 1981. Rapid modulation of acetylcholine receptor synthesis. FEBS Letters 135, 103-106.

Nisson Schechter, Indhira C. Handy, Leo Pezzementi, and Jakob Schmidt. 1978. Distribution of a-bungarotoxin binding sites in the central nervous system and the peripheral organs of the rat. Toxicon 16, 245-251.

ABSTRACTS

Leo Pezzementi, Abigail E. Dy, Lauren Nicholas S. Herrera, Avirath N. Purohit, Megan M. Sandlin, Janelle T. West. 2012. Do the MRL proteins – MIG-10, RIAM, and Lamellipodin – interact with acetylcholinesterase and butrylcholinesterase? Eleventh International Meeting on Cholinesterases (Kazan, Russia): Program and Abstracts, 103.

Leo Pezzementi, Nicolas Lenfant, and Arnaud Chatonnet. 2012. Cholinesterases in Saccoglossus kowalevskii (hemicordata): cloning, in vitro expression, and molecular characterisation. Eleventh International Meeting on cholinesterases (Kazan, Russia): Program and Abstracts, 217.

Leo Pezzementi and Arnaud Chatonnet. 2009. Evolution of vertebrate cholinesterases: an intermediate cholinesterase from the teleost fish, the medaka (Oryzias latipes). Tenth International Meeting on cholinesterases (Sibenik, Croatia): Program and Abstracts, 34.

Leo Pezzementi and Arnaud Chatonnet. 2009. Evolution of cholinesterases in the animal kingdom. Tenth International Meeting on cholinesterases (Sibenik, Croatia): Program and Abstracts, 34.

Leo Pezzementi, Brian Davis, Robert Kress, Brendan Burn, Ashley Russell, Elizabeth Molony, Tia Barclay, Jeffrey Lucas, Julie Johnson, Brian Perrin, Claire Anderson, Igor Tsigelny, Eric Krejci. 2009. The effect of Ser20 T-peptide mutations on the tetramerization of Ciona intestinalis AChE and its association with the proline-rich membrane anchor, PRiMA. Tenth International Meeting on cholinesterases (Sibenik): Program and Abstracts, 84-85.

Adam Frederick, Igor Tsigelny, Frances Cohenour, Christopher Spiker, Eric Krejci, Arnaud Chatonnet, Stefan Bourgoin, Greg Richards, Tessa Allen, Mary Hollace Whitlock, and Leo Pezzementi. 2007. In vitro expression, kinetic, pharmacologic, molecular, and evolutionary anayses, and molecular modeling of a recombinant acetylcholinesterase from the invertebrate urochordate Ciona intestinalis: assembly of asymmetric forms with ColQ. Ninth International Meeting on Cholinesterases (Suzhou, China): Program Book, 24.

Melissa Rowland, Igor Tsigelny, Matthew Wolfe, and Leo Pezzementi. 2007. Inactivation of an invertebrate acetylcholinesterase by sulfhydryl reagents and elevated temperature. Ninth International Meeting on Cholinesterases (Suzhou, China): Program Book, 87.

Natalie A. Jennings, Leo Pezzementi, Micki L. Powell, A.L. Lawrence, and Stephen A. Watts. 2007. Characterization of acetylcholinesterase in the sea urchin Lytechinus variegates. Ninth International Meeting on Cholinesterases (Suzhou, China): Program Book, 94.

Raj Patel, Rachel Sander, Lance Brown, Stephanie Baker, Igor Tsigelny, and Leo Pezzementi. 2007. A tryptophan in the bottleneck of the catalytic gorge of an invertebrate acetylcholinesterase confers resistance to carbamates and organophosphate inhibitors. Ninth International Meeting on Cholinesterases (Suzhou, China): Program Book, 114.

Leo Pezzementi, Kim Johnson, Justin Cotney, Andrew Barker, and Elizabeth Manning. 2004. Amino acids involved in substrate and inhibitor specificity in cholinesterase 2 from amphioxus. In Cholinesterases in the Second Millennium: Biomolecular and Pathological Aspects, (N.C. Inestrosa and E.O. Campos, eds.), MIFAB: Santiago, Chile, p.370.

Leo Pezzementi, Justin Cotney, and Brett Earley. 2002. Probing the molcular basis of the substrate and inhibitor specificities of cholinesterase 1 and cholinesterase 2 from amphioxus. Experimental Biology, ASBMB, 2002, 426.1.

Leo Pezzementi and Joy F. Johnson. 2002. A collaborative recombinant DNA course with laboratory. Experimental Biology, ASBMB, 2002, 684.8.

Leo Pezzementi and Larry Fish. 2001. A collaborative recombinant DNA course with laboratory. The Journal of the Alabama Academy of Science, 72, 125.

Leo Pezzementi, David Sutherland, Michael Sanders, Weily Soong, Daniel Milner, James Scott McClellan, Mathew Sapp, William Blake Coblentz, Gabriel Rulewicz, and Sarah Merritt. 1998. Structure and function of cholinesterases from agnathans and cephalochordates: implications for the evolution of the cholinesterases. The Sixth International Meeting on Cholinesterases (La Jolla, CA): Program and Abstracts, 5.

Leo Pezzementi, David Sutherland, Michael Sanders, Weily Soong, Daniel Milner, James Scott McClellan, Mathew Sapp, William Blake Coblentz, Gabriel Rulewicz, and Sarah Merritt. 1998. Pharmacological and molecular analysis of cholinesterases from agnathans and cephalochordates: implications for the evolution of resistance to cholinesterase inhibitors. Sixth International Meeting on Cholinesterases (La Jolla, CA): Program and Abstracts, 17.

James Scott McClellan, William Blake Coblentz, Mathew Sapp, Gabriel Rulewicz, David Isaac Gaines, Ashley Hawkins, Caroline Ozment, Amy Bearden, Sarah Merritt, John Cunningham, Elizabeth Palmer, Amir Contractor, and Leo Pezzementi. 1998. cDNA cloning, in vitro expression, and biochemical characterization of cholinesterase 1 and cholinesterase 2 from amphioxus: comparison with cholinesterase 1 and cholinesterase 2 produced in vivo. Sixth International Meeting on Cholinesterases (La Jolla, CA): Program and Abstracts, A5.

Leo Pezzementi, Rick Jotani, Bonnie Mathews, Danny Milner, and Weily Soong. 1995 Is butyrylcholinesterase present in primitive chordates? Soc. Neurosci. Abstr. 20, 839.4.

Leo Pezzementi, Michael Sanders, Michael Miller, Kristin Glaese, and Lee Ann Shannon. 1994. Identification of globular and asymmetric forms of an intermediate cholinesterase in amphioxus: implications for the evolution of the cholinesterases in the vertebrates. Soc. Neurosci. Abstr. 20, 409.10.

Leo Pezzementi, Weily Soong, David Sutherland, Michael Sanders and Harry Giles. 1993. Evolutionary origins of cholinesterase duality in the vertebrates. Soc. Neurosci. Abstr. 19, 378.12.

Leo Pezzementi, Weily Soong, David Sutherland, Michael Sanders and Harry Giles. 1993. Molecular probing of the evolutionary origins of cholinesterase duality (Abstr.). J. Neurochem. 61 (Suppl.), S146D.

Leo Pezzementi, Michael Sanders, Todd Jenkins, Jean-Pierre Toutant and Ronald J. Bradley. 1990. Structure and Function of cholinesterase from amphioxus. Third International Meeting on Cholinesterases (La Grande Motte, France), p.5.

Leo Pezzementi. 1989. Evolutionary and developmental implications of the structure of acetylcholinesterase from the lamprey Petromyzon marinus. J. Alabama Acad. Sci. 60, 125.

Leo Pezzementi, Hugh Nickson, Robert Dunn and Ronald J. Bradley. 1987. Molecular forms of acetylcholinesterase from adult lamprey brain and ammocoete skeletal muscle. Soc. Neurosci. Abstr. 13, 286.10.

Leo Pezzementi, Ellen Reinheimer and Maureen Pezzementi. 1985. Acetylcholinesterase from lamprey skeletal muscle is found in globular and asymmetric forms. Soc. Neurosci. Abstr. 11, 12.17.

Leo Pezzementi. 1984. Acetylcholinesterase from the skeletal muscle of the lamprey. 1984. Soc. Neurosci. Abstr. 10, 140.7.

Mark Schneider, Bih-Hwa Shieh, Leo Pezzementi and Jakob Schmidt. 1983. The effect of trifluoperazine on AChR synthesis in cultured chick myotubes. Soc. Neurosci. Abstr. 9, 18.1.

Bih-Hwa Shieh, Leo Pezzementi and Jakob Schmidt. 1982. Membrane potential and the regulation of AChR synthesis in embryonic chick skeletal muscle cells. Soc. Neurosci. Abstr. 8, 205.9

Leo Pezzementi and Jakob Schmidt. 1981. Acetylcholine receptor synthesis of chick skeletal muscle cell cultures is altered by ryanodine. Soc. Neurosci. Abstr. 7, 259.4.

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